TABLE 2.
Formulation | at 50% (h) | bDE | cQ2 (mg) | dQ8 (mg) | Difference factor | Similarity factor |
---|---|---|---|---|---|---|
F1 | 4 | 56.2 | 20.41±3.15 | 60.92±2.72 | 37 | 31.65 |
F2 | 3 | 65.06 | 24.36±2.04 | 71.39 ±2.06 | 25.97 | 40.4 |
F3 | 3 | 81.43 | 36.08±1.99 | 84.61±0.66 | 17.16 | 48.07 |
F4 | 2.5 | 88.57 | 46.75±1.10 | 94.41±0.61 | 19.78 | 43.62 |
Physical mixture | 2.5 | 95 | 40.60±2.88 | 103.89±1.06 | 13.76 | 53.6 |
Medectin® | 2.5 | 82.79 | 38.10±1.52 | 60.41±1.88 | 0 | 100 |