Table 1.
Histological stages of human breast cancer.
| Stage | TNM | Description | 5-year survival |
|---|---|---|---|
| 0 | Tis N0 M0 | Carcinoma in situ. No tumor in regional lymph nodes, No distant metastases. | 99% |
| I | T1 N0 M0 | Tumor is less than or equal to 2 centimeters, No tumor in regional lymph nodes, No distant metastases. | 92% |
| IIA | T0 N1 M0 | • No evidence of primary tumor, metastases to movable ipsilateral nodes, No distant metastases. | 82% |
| T1 N1 M0 | • Tumor is less than or equal to 2 centimeters, metastases to movable ipsilateral nodes, No distant metastases. | ||
| T2 N0 M0 | • Tumor is between 2 and 5 centimeters, No tumor is regional lymph nodes, No distant metastases. | ||
| IIB | T2 N1 M0 | • Tumor is between 2 and 5 centimeters, metastases to movable ipsilateral nodes, No distant metastases. | 65% |
| T3 N0 M0 | • Tumor is over 5 centimeters, No tumor in regional lymph nodes, No distant metastases. | ||
| IIIA | T0 N2 M0 | • No evidence of primary tumor, metastases to fixed ipsilateral nodes, No distant metastases. | 47% |
| T1 N2 M0 | • Tumor is less than or equal to 2 centimeters, metastases to fixed ipsilateral nodes, No distant metastases. | ||
| T2 N2 M0 | • Tumor is between 2 and 5 centimeters, metastases to fixed ipsilateral nodes, No distant metastases. | ||
| T3 N1, N2 M0 | • Tumor is over 5 centimeters, metastases to movable or fixed ipsilateral nodes, No distant metastases. | ||
| IIIB | T4 Any N M0 | • Tumor extends to chest wall, any nodal involvement, No distant metastases. | 44% |
| Any T N3 M0 | • Any primary tumor involvement, metastases. to ipsilateral internal mammary nodes, No distant metastases. | ||
| IV | Any T Any N M1 | Any primary tumor involvement, any nodal involvement, distant metastases. | 14% |
Abbreviations: T, status of primary tumor; N, regional lymph nodes; M, distant metastases.