Table 4.
Distributions of the MGMT combined genotypes between the SCCHN cases and controls
| No. of risk genotypesa | Cases (n = 721) |
Controls (n = 1,234) |
Pb | ||
|---|---|---|---|---|---|
| n | % | n | % | ||
| Ordinal | 0.014 | ||||
| 0 | 22 | 3.0 | 65 | 5.3 | |
| 1 | 105 | 14.5 | 165 | 13.4 | |
| 2 | 162 | 22.5 | 337 | 27.3 | |
| 3 | 353 | 49.0 | 542 | 43.9 | |
| 4 | 79 | 11.0 | 125 | 10.1 | |
| Dichotomized groups | 0.012 | ||||
| 0-2 | 289 | 40.1 | 567 | 46.0 | |
| 3-4 | 432 | 59.9 | 667 | 54.0 | |
a
The number represents the numbers of risk genotypes; the risk genotypes used for the calculation were 16195CC, 16286CC, 45996GT+TT, and 46346CA+AA genotypes).
b
Two-sided chi-square test for the combined genotype distributions between the cases and controls.