. Author manuscript; available in PMC: 2011 May 4.

Published in final edited form as: DNA Repair (Amst). 2010 Mar 4;9(5):558–566. doi: 10.1016/j.dnarep.2010.02.006

Table 7.

False positive reporting probability values for Associations between the combined genotypes of MGMT and SCCHN risk

Combined Genotypes	Positive OR and 95% CI^a	P^b	Statistical Power^c	Prior probability
Combined Genotypes	Positive OR and 95% CI^a	P^b	Statistical Power^c	0.25	0.1	0.01	0.001	0.0001
0-2 risk genotypes vs. 3-4 risk genotypes
All subjects	1.27 (1.06-1.53)	0.012	0.958	0.036	0.101	0.553	0.926	0.992
Ever smoker	1.26 (1.01-1.57)	0.037	0.937	0.106	0.262	0.796	0.975	0.997
Ever drinking	1.28 (1.03-1.59)	0.025	0.923	0.075	0.196	0.728	0.964	0.996
Oropharynx	1.44 (1.12-1.85)	0.004	0.615	0.019	0.055	0.392	0.867	0.985
Orophasyngeal Cancer
Involvement of regional lymph nodes(N_1-3)	1.51 (1.16-1.98)	0.003	0.499	0.018	0.051	0.373	0.857	0.984
Tumor stage T_1-2	1.73 (1.26-2.37)	0.001	0.227	0.013	0.038	0.304	0.815	0.978

The crude OR.

The omnibus chi-square test of the combination genotype distributions.

Calculated using study subjects to detect an OR of 1.5 with the common combined genotype used as the reference.