Table 2.
Simulated median ranks of a true susceptibility SNP with a recessive effect and log-odds-ratio value of log(3) for alternative tests. The results are based on 50 simulated datasets, each of which has approximately 550 cases and 550 controls and 450,000 SNPs.
MAF | Prospective | Retrospective | Empirical-Bayes |
---|---|---|---|
0.1 | 112163 | 8117 | 44319 |
0.2 | 1888 | 203 | 52 |
0.3 | 656 | 210 | 27 |
0.4 | 15 | 82 | 2 |