Table 2.
Association between allele type of the PATRR22 polymorphism and frequency of de novo translocation
| Case | Genotype of the AT-rich region | PATRR11 genotype | Frequency | Positive PCR | Allelic origin |
||
|---|---|---|---|---|---|---|---|
| A | B | C | |||||
| 1 | A/C | L/L | 2.24 × 10−5 | 23/44 | 1 (4%) | — | 22 (96%) |
| 2 | A/C | L/L | 5.55 × 10−5 | 30/50 | 5 (17%) | — | 25 (83%) |
| 3 | A/C | L/L | 6.01 × 10−6 | 9/50 | 2 (22%) | — | 7 (78%) |
| 10 | A/C | L/AS | 1.45 × 10−5 | 19/50 | 1 (5%) | — | 18 (95%) |
| 4 | B/C | L/L | 9.18 × 10−5 | 39/50 | — | 20 (51%) | 19 (49%) |
| 5 | B/C | L/L | 2.55 × 10−5 | 35/51 | — | 17 (49%) | 18 (51%) |
| 6 | B/C | L/L | 1.65 × 10−4 | 21/50 | — | 9 (43%) | 12 (57%) |
| 11 | B/C | L/S | 1.35 × 10−5 | 18/50 | — | 7 (39%) | 11 (61%) |
| 12 | B/C | L/S | 1.60 × 10−5 | 30/73 | — | 14 (47%) | 16 (53%) |
| 13 | B/C | L/AS | 8.72 × 10−6 | 22/88 | — | 10 (45%) | 12 (55%) |
L, long PATRR; S, symmetric short PATRR; AS, asymmetric short PATRR.