Figure 2.
MTMR14 morphants fail to respond to high-frequency electrical stimulation. In response to 5 ms depolarizing current injections to +60 mV, skeletal muscle from control embryos routinely contracted above 20 Hz for 10 s (n = 6/6). In contrast, skeletal muscle from MTMR14 morphants failed to contract at 20 Hz (n = 0/6). Values represent the average ± SEM at which muscle could sustain contractions in response to electrical stimuli.