Maximum principal strain, maximum principal stress, and tangent moduli distributions (error bars show the 25th, 50th, and 75th percentiles) plotted by age group for both scleral regions (peripapillary and peripheral) at the following IOPs: 5, 10, 30 and 45 mmHg. On average, sclera from the old monkeys exhibited higher tangent moduli and stress, but lower strain than that from the young monkeys. Note the nonlinear relationship between IOP and strain, which is due to the increase of tangent moduli with IOP (the sclera stiffens as IOP increases).