Table 5.

Determinants of Cystatin C in Multiple Linear Regression

	T1D		Non-DM
Variable	B estimate	P value	B estimate	P value	Interaction P value
Gender (female vs. male)	−0.120	<0.0001	−0.038	0.0001	0.0003
HDLa	−0.021	0.02	−0.012	0.008	0.35
BMIa	−0.025	0.02	0.009	0.02	0.003
PAI-1a	−0.001	0.90	0.013	0.0007	0.20
Fibrinogena	0.031	0.002	0.009	0.01	0.04
Serum creatinineb	0.243	<0.0001	0.058	<0.0001	<0.0001
Homocysteineb	0.017	0.11	0.022	<0.0001	0.64
AERb	0.020	0.01	−0.013	0.04	0.001

SD: BMI = 4.7 kg/m²; HDL = 15.7 mg/dL; PAI-1 = 25.1 ng/mL; fibrinogen = 63.6 mg/dL; serum creatinine = 1.2 mg/dL; homocysteine = 1.3 nmol/L; AER = 3.1 μg/min.

^aEstimate per SD increase.

^bEstimate per SD increase of the log-transformed variable.