Skip to main content
. 2010 Jun 10;5(6):e11065. doi: 10.1371/journal.pone.0011065

Figure 5. Lactobacillus acidophilus NCFM induces IFN-β in dendritic cells.

Figure 5

The IFN-β encoding gene is strongly up-regulated in L .acidophilus NCFM stimulated dendritic cells and responsible for the expression of the chemokines Cxcl10 and Ccl12. A. Expression of the IFN-β encoding gene over time in dendritic cells upon stimulation with L. acidophilus NCFM and B. bifidum Z9. B. Inhibition of IFN-β activity induced by L. acidophilus NCFM by addition of polyclonal IFN-β antibodies measured via the gene expression of the chemokine Cxcl10 after 10 h and C. via the gene expression of the chemokine Ccl12 after 10 h and D. via protein production of Cxcl10 in the supernatant after 24 h of stimulation by ELISA (P<0.01).