Table 4. Inhibitory Effects of Bifidobacterium bifidum Z9 on the Cytokine Expression in Lactobacillus acidophilus NCFM stimulated Dendritic Cells.
Ensembl Gene Nr | Annotation | L. acidophilus | B. bifidum | L. acidophilus + B. bifidum | Name |
00000048806 | Ifnb1 | 2.5 | 0.9 | 0.48 | Interferon beta 1 |
00000004296 | Il12b | 5.5 | 4.3 | 5 | Interleukin 12b |
00000031712 | Il15 | 2.7 | 1.8 | 2.4 | Interleukin 15 |
00000024401 | Tnf | 2.1 | 1.3 | 1.7 | Tumor necrosis factor alpha |
00000039217 | Il18 | 2.0 | 1.0 | 1.4 | Interleukin 18 |
00000025383 | Il23a | 1.0 | 0.37 | 0.68 | Interleukin 23a |
00000027776 | Il12a | 0.77 | 0.6 | 0.59 | Interleukin 12a |
Data indicates gene expression fold changes of dendritic cells stimulated with L. acidophilus NCFM, B. bifidum Z9 and both strains in combination in comparison with un-stimulated dendritic cells measured on Affymetrix microarrays. Foldchanges are log2 relative to control.