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. 2010 Jun 10;6(6):e1000984. doi: 10.1371/journal.pgen.1000984

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White et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) PKCδ (green) and mitochondria (red) in control normal fibroblasts. (B) PKCδ (green) in SCA10 fibroblast (punctate aggregates), primarily outside nuclei. Merge green (PKCδ with red (mitochondria) is seen as yellow/orange fluorescence. (C) PKCδ (green) and mitochondria (red) in the cortex of the control transgenic mouse brain expressing 12 ATTCT repeats. (D) PKCδ (green) and mitochondria (red) in SCA10 transgenic mouse cortex expressing ∼500 AUUCU repeats. Merge of green (PKCδ) and red (mitochondria) is shown as yellow/orange fluorescence in cortex of the SCA10 transgenic mice.