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. 2010 Jun 10;6(6):e1000812. doi: 10.1371/journal.pcbi.1000812

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Baldazzi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The networks are computed from the models and , taking into account allosteric effects (see Sec. 3 of Text S3). The boxes represent fast coupling species, mediating the influence of metabolism and signal transduction on gene expression: CrpcAMP, free FruR, RpoSRssB*, and DNA supercoiling. The influence of the enzymes and other slow species on the concentration of the fast coupling species are represented by +/− signs.

Inline graphic — The networks are computed from the models and , taking into account allosteric effects (see Sec. 3 of Text S3). The boxes represent fast coupling species, mediating the influence of metabolism and signal transduction on gene expression: CrpcAMP, free FruR, RpoSRssB*, and DNA supercoiling. The influence of the enzymes and other slow species on the concentration of the fast coupling species are represented by +/− signs.