Figure 5. Distribution of Argonaute-associated siRNAs in telomere-adjacent regions.

The diagrams represent subtelomeric regions at the indicated chromosome arms. The rulers indicate the distance from a continuous array of telomeric repeats, open boxes mark positions of telomeric repeats intermingled within subtelomeric sequences. Only chromosome arms containing siRNAs detected within 5 kb from telomeres are shown. The position and orientation of AGO-associated siRNAs is indicated by colored bars. Only siRNAs that aligned to unique locations are included (Table S2). The TERRA and ARRET transcripts detected by strand-specific RT-PCR are depicted by a red arrow.