Table 2.
Hazard ratios and 95% confidence intervals (CI) for the association between dietary lignan intake and death from all causes or breast cancer in the Western New York Exposures and Breast Cancer Study
| Lignan intake (mcg/d) | Events (n) | Hazard ratio (95% CI) |
|---|---|---|
| Premenopausal (n = 315) | ||
| All cause mortality | ||
| < 128 | 7 | 1.00 |
| 128–181 | 12 | 1.54 (0.59–3.98) |
| 181–257 | 7 | 0.88 (0.30–2.58) |
| >257 | 18 | 2.14 (0.82–5.56) |
| P for trend | 0.02 | |
| Breast cancer mortality | ||
| < 128 | 6 | 1.00 |
| 128–181 | 12 | 1.70 (0.62–4.62) |
| 181–257 | 6 | 0.83 (0.26–2.67) |
| >257 | 14 | 1.84 (0.65–5.27) |
| P for trend | 0.03 | |
| Postmenopausal (n = 807) | ||
| All cause mortality | ||
| < 155 | 33 | 1.00 |
| 155–227 | 33 | 0.91 (0.55–1.52) |
| 227–318 | 29 | 0.78 (0.46–1.33) |
| >318 | 21 | 0.49 (0.26–0.91) |
| P for trend | 0.02 | |
| Breast cancer mortality | ||
| < 155 | 18 | 1.00 |
| 155–227 | 20 | 0.94 (0.48–1.87) |
| 227–318 | 11 | 0.51 (0.23–1.15) |
| >318 | 7 | 0.29 (0.11–0.76) |
| P for trend | 0.01 | |
Cox proportional hazards adjusting for age, race, total energy, stage at diagnosis, body mass index, and education