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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Gastroenterology. 2010 Feb 23;138(7):2531–2540.e4. doi: 10.1053/j.gastro.2010.02.043

Figure 2. β1-Itgflox/flox;Ptf1a-Cre pancreata degenerate with age.

Figure 2

(A) Gross phenotype of 1 year-old wild type and β1-Itg flox/flox;Ptf1a-Cre pancreata. (B) Pancreas/body mass ratio in β1-Itg flox/flox;Ptf1a-Cre mice at 3 weeks (n=7, each group) and 7-14 weeks of age (n=4, each group) was ~70% that of wild type mice. By 12 months, relative pancreatic mass in β1-Itg flox/flox;Ptf1a-Cre mice decreased to ~25% of control (P<0.05, n=9 for wild type, n=15 for β1-null), which remains stable at 20 months (n=9, each group.