. Author manuscript; available in PMC: 2010 Dec 1.

Published in final edited form as: Gene Ther. 2010 Mar 18;17(6):799–804. doi: 10.1038/gt.2010.24

Table 3.

Proximity of vector insertions to oncogenes (n.s. = non significant).

	CatPac vector (n=184)	Matching Random	p-value	Control MoMLV (n=175)	Matching Random	p-value	p-value CatPac vector vs. MoMLV
Number of oncogenes w/ in 30 kb of one or more integration sites	12	2.8	p < 0.0001	7	2.7	p ≤ 0.0201	p ≤ 0.3525 ^(n.s.)
Number of genes w/ in 30 kb of one or more integration sites	288	132.6	p < 0.0001	268	126.4	p < 0.0001	p ≤ 0.4181 ^(n.s.)
Genes that are oncogenes w/ in 30 Kb of integration site	4.2%	2.2%	p ≤ 0.0705 ^(n.s.)	2.6%	2.1%	p ≤ 0.3216 ^(n.s.)	p ≤ 0.4385 ^(n.s.)

Number of integration sites w/in 30 kb of one or more oncogenes	12	2.8	p < 0.0001	6	2.7	p ≤ 0.0562 ^(n.s.)	p ≤ 0.2711 ^(n.s.)
Number of integration sites w/i 30 kb of one or more genes	150	96.5	p < 0.0001	156	91.9	p < 0.0001	p ≤ 0.0593 ^(n.s.)
Sites w/ in 30 Kb of a gene that is an oncogene	8.0%	2.9%	p ≤ 0.0075	3.9%	2.9%	p ≤ 0.2836 ^(n.s.)	p ≤ 0.1933 ^(n.s.)