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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Mol Cell Cardiol. 2010 Feb 6;49(1):41–47. doi: 10.1016/j.yjmcc.2010.02.001

Figure 3.

Figure 3

Top, Fluorescence images of TSQ 5 min after the onset of reperfusion in isolated rat hearts. Myocardial tissue Cryosections were stained with the free zinc indicator TSQ. Bottom, Summarized data for TSQ fluorescence intensity 5 min after the onset of reperfusion. Compared to the control (n = 3), the heart treated with NECA (100 nM, n = 3) showed a marked increase in TSQ fluorescence intensity at reperfusion, indicating that NECA increases intracellular free zinc at reperfusion. The effect of NECA on TSQ fluorescence was reversed by the zinc chelator TPEN (10 μM). * p < 0.05 vs. control; # p < 0.05 vs. NECA.