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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Mol Cell Cardiol. 2010 Feb 6;49(1):41–47. doi: 10.1016/j.yjmcc.2010.02.001

Figure 4.

Figure 4

Summarized data for Newport Green DCF fluorescence intensity 10 min after exposure to NECA in isolated rat cardiomyocytes. NECA (100 nM, n = 6) markedly increased the fluorescence intensity compared to control (n = 6), an effect that was reversed by both the NOS inhibitor L-NAME (200 μM, n = 6) and the PKG inhibitor KT5823 (1 μM, n = 6), indicating that NECA mobilizes intracellular zinc through the NO/PKG signaling pathway. At least 5 cells were analyzed in each experiment. * p < 0.05 vs. control; # p < 0.05 vs. NECA.