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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Microbes Infect. 2010 Mar 7;12(6):476–487. doi: 10.1016/j.micinf.2010.02.009

Fig. 1.

Fig. 1

(A) Genetic organization of the N. meningitidis capsule gene complex (cps) and the E. coli K1 capsule (kps) locus. The genes responsible for capsular biosynthesis (dotted arrows, syn (sia)ABCD), capsule transport (hatched arrows, ctrABCDEF; ctrEF were formerly known as lipA and lipB), and the E. coli K1 homologues of each are shown. The location of NMB0065 (black arrow) within the cps complex in the serogroup B strain NMB was similar to that of the published serogroup B MC58 genome sequence[45]. An IS1016-like transposase (indicated as a black bar) is present upstream of the NMB0065 homologue in serogroups Y and W135. OatC and OatWY are O-acetyltransferases specific for capsules of serogroup C and groups Y and W135, respectively. (B) The Clustal W protein sequence alignment of NMB0065 and NeuE [46]. The predicted polyprenyl-binding motif (PIRS) motif sequence in NeuE is highlighted in bold.