. Author manuscript; available in PMC: 2011 Jun 1.

Published in final edited form as: Gastroenterology. 2010 Feb 20;138(7):2332–2340. doi: 10.1053/j.gastro.2010.02.015

Table 5.

Comparison of ICT lure performance between patients who developed overt HE and those who remained overt HE-free

	Developed overt HE (n=15)	Did not develop overt HE (n=44)	P value between groups
Total lures on Visit 1 minus Visit 2	5.2	0.2	0.0002
1^st visit ΔL_1–2	3.1	2.1	0.56
2^nd visit ΔL_1–2	0.3	1.8	0.0001
Change in ΔL_1–2 between visits	2.8	0.3	0.0001

There was a significant change over time in total lures in patients who developed their first overt HE episode compared to those who did not. ΔL_1–2: Lures in runs I–III (1^st half) minus lures in runs IV–VI (2^nd half), a higher number indicates learning; this was similar between groups at baseline. Once they developed overt HE, ΔL_1–2 declined while it remained stable in those who did not develop overt HE and the change in ΔL_1–2 i.e. extent of change of leaning ability was also significantly different. Overt HE: overt hepatic encephalopathy adequately controlled on treatment, ICT: inhibitory control test.