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. 2010 Apr 27;102(12):1681–1686. doi: 10.1038/sj.bjc.6605660

Table 1. Lung cancer CT screening: results of observational studies.

            Lung cancers
  Subjects Age (years) a NSM b p-y c CT lesions d Baseline e Stage I f First repeat g
Henschke et al, 1999 1000 67 0 45 233 (23) 27 (2.7) 85
Sone et al, 2001 5483 64 54 588 (11) 23 (0.4) 100 27 (0.5)
Nawa et al, 2002 7956 56 38 541 (7) 36 (0.5) 78 4 (0.1)
Sobue et al, 2002 1611 59 14 186 (12) 14 (0.9) 71 22 (1.4)
Diederich et al, 2004 817 53 0 45 350 (43) 12 (1.5) 64
Swensen et al, 2003 1520 59 0 45 780 (51) 27 (1.7) 74 13 (0.9)
Pastorino et al, 2003 1035 58 0 40 199 (19) 11 (1.1) 55 11 (1.1)
Bastarrika et al, 2005 911 55 0 30 291 (32) 12 (1.3) 83 2 (0.2)
Chong et al, 2005 6406 55 23 2,255 (35) 23 (0.4) 56
Novello et al, 2005 519 59 0 241 (47) 5 (1.0) 67 3 (0.6)
MacRedmond et al, 2006 449 55 0 45 111 (25) 2 (0.4) 50 4 (0.9)
I-ELCAP 2006 31 567 61 17 30 4186 (13) 410 (1.3) 85 74 (0.2)
Veronesi et al, 2008 5201 58 0 44 2754 (53) 55 (1.1) 66 37 (0.7)
                 
Overall 64 475 59 20 12 715 (20) 657 (1.0) 81 197 (0.3)

Abbreviations: CT=computed tomography; NSM=non-smokers; p-y=pack-years.

a

Median age of participants.

b

Proportion of non-smokers.

c

Median pack-years.

d

Subjects with suspicious non-calcified solid lesions (percentage of participants).

e

Lung cancers detected at baseline (percentage of participants).

f

Percentage of lung cancers detected in stage I at baseline.

g

Lung cancers detected at first annual CT repeat.