Table 2. Lung cancer CT screening: randomised studies.

Study	Country	Study design	Year started	Subjects enrolled	Age range (years)	Years screen
LSS (Gohagan et al, 2005)	USA	CT vs CXR	2000	3318	55–74	2
DANTE (Infante et al, 2008)	Italy	CT vs obs	2001	2472	60–74	4
NLST (Clark et al, 2008)	USA	CT vs CXR	2002	53 000	55–74	3
NELSON (van den Bergh et al, 2008)	NL–B	CT vs obs	2003	15 822	50–74	5
ITALUNG (Lopes Pegna et al, 2009)	Italy	CT vs obs	2004	3206	55–69	5
DLCST (Pedersen et al, 2009)	DK	CT vs obs	2004	4104	50–70	5
MILD (Pastorino et al, 2006)	Italy	CT vs obs	2005	4479	49–75	10
LUSI (Becker et al, 2008)	Germany	CT vs obs	2007	4000	50–69	5

Abbreviation: CT=computed tomography; CXR=chest X-ray; DLCST=Danish Lung Cancer Screening Trial; LSS=Lung Screening Study; MILD=Multicentric Italian Lung Detection; NL–BM=the Netherlands and Belgium; NLST=National Lung Screening Trial; obs=observational studies.