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. 2010 Jun 8;102(12):1692–1698. doi: 10.1038/sj.bjc.6605705

Table 3. Univariate analyses of clinicopathologic parameters on recurrence-free and overall survival in patients with adenocarcinoma.

  Adenocarcinoma (n=222)
    Recurrence-free survival
Overall survival
Variables N (%) 5-year rate (%) P-value 5-year rate (%) P-value
Age, years          
 As continuous variable 222 (100)   0.153   0.073
 <30 5 (2.3) 80 0.250 80 0.096
 30–49 141 (63.5) 89   93  
 >50 76 (34.2) 81   86  
           
FIGO stage          
 IA2 8 (3.6%) 100 <0.001 100 <0.001
 IB1–IB2 195 (87.8%) 89   92  
 IIA 19 (8.6%) 52   65  
           
Histologic subtype
 Mucinous 203 (16.7%) 87 0.373 90 0.425
 Endometrioid 14 (1.1%) 77   84  
 Serou 2 (0.2%) 50   50  
 Mixed 3 (0.2%) 100   100  
           
Grade of differentiation a
 Well 63 (29.0) 88 0.688 90 0.532
 Moderately 94 (43.3) 83   91  
 Poorly 60 (27.6) 87   89  
           
Tumour size, cm          
 ⩽2 108 (48.6) 91 0.041 95 0.033
 2–4 94 (42.3) 82   85  
 4–6 20 (9.0) 77   90  
 >6 0 (0.0)    
           
Depth of stromal invasion
 ⩽1/2 135 (60.8) 92 0.002 94 0.008
 >1/2 87 (39.2) 78   84  
           
Parametrial involvement
 No 200 (90.1) 89 <0.001 92 <0.001
 Yes 22 (9.9) 55   66  
           
Resection margin
 Negative 218 (98.2) 87 0.013 91 0.005
 Positive 4 (1.8) 38   38  
           
LVSI          
 No 189 (85.1) 88 0.033 92 0.026
 Yes 33 (14.9) 75   80  
           
Lymph node metastasis
 No 188 (84.7) 90 <0.001 94 <0.001
 Yes 34 (15.3) 66   69  
           
Adjuvant treatment
 None 159 (71.6) 89 0.003 94 <0.001
 Chemotherapy 20 (9.0) 88   95  
 Radiation therapy 26 (11.7) 76   77  
 CCRT 11 (7.7) 71   70  

Abbreviations: CCRT=concurrent chemoradiation therapy; FIGO=International Federation of Obstetrics and Gynecology; LVSI=lymphovascular space invasion.

a

Grade of differentiation was undetermined in 21 patients.