Table 1. TGFβ1-induced candidate genes involved in switch to singlecell motility.
Gene name | Biological processes/ function/ pathway |
---|---|
RhoC | Motility, actin cytoskeleton, adhesion, force generation |
NEDD9 | Cell shape/plasticity, cell adhesion and actin cytoskeleton |
m-RIP (RhoIP3) | Regulation of stress fibers formation, force generation |
FARP-1 | Rho exchange factor |
EGFR (ErbB1) | Cell migration, adhesion, proliferation |
c-jun | AP-1 signaling, invasion, tumor progression |