Table 5.
Comparison between systemic, polyarticular, oligoarticular juvenile idiopathic arthritis subtypes regarding demographic, clinical, laboratory and magnetic resonance imaging findings
| Variables | Systemic JIA Mean±SD | Polyarticular JIA Mean±SD | Oligoart. JIA Mean±SD | F-value | p-value | Sig. |
|---|---|---|---|---|---|---|
| Age (years) | 12.16±4.07 | 14.78±1.83 | 14.33±1.52 | 1.7 | >0.05 | NS |
| Age at dis.ons (years) | 8.00±4.09 | 10.03±2.25 | 7.00±3.60 | 1.9 | >0.05 | NS |
| Dis. duration (years) | 4.16±0.76 | 4.75±2.43 | 7.33±2.51 | 1.7 | >0.05 | NS |
| No. of active jts | 2.00±1.0 | 5.28±0.46 | 1.66±0.57 | 77.2 | <0.001 | HS |
| Dis. activity score | 4.33±0.57 | 3.42±1.01 | 2.00±0.00 | 5.09 | <0.05 | S |
| C-HAQ | 1.33±0.28 | 0.99±0.47 | 0.46±0.30 | 2.9 | >0.05 | NS |
| Pain score | 1.83±0.73 | 1.50±0.51 | 0.70±0.17 | 3.9 | <0.05 | S |
| MIO (mm) | 37.33±0.57 | 42.85±4.14 | 49.33±3.21 | 7.5 | <0.05 | S |
| ESR (mm h−1) | 106.30±35.92 | 61.50±29.2 | 15.33±4.16 | 7.6 | <0.05 | S |
| CRP (mg mL−1) | 35.00±2.0 | 22.28±10.06 | 6.66±0.57 | 7.7 | <0.05 | S |
| S.S100A12 (ng mL−1) | 1070.00±480.3 | 691.07±295.61 | 145.00±8.66 | 6.9 | <0.05 | S |
| Syn. enhan. score | 4.00±0.0 | 2.57±1.65 | 1.33±1.15 | 2.3 | >0.05 | NS |
| Effusion score | 3.33±0.57 | 1.28±1.32 | 0.00±0.0 | 6.2 | <0.05 | S |
| Pannus score | 2.66±1.52 | 0.28±0.72 | 0.00±0.0 | 11.2 | <0.05 | S |
| Erosion score | 2.33±1.15 | 0.14±0.36 | 0.00±0.0 | 24.3 | <0.001 | HS |
| Total MRI score | 12.33±2.08 | 4.28±2.99 | 1.33±1.15 | 13.8 | <0.001 | HS |
Oligoart: Oligoarticular, JIA: Juvenile idiopathic arthritis, Dis: Disease, ons: Onset, No: Number, Jts: Joints,C-HAQ: Child health assessment questionnaire, MIO: Maximal interincisal opening, ESR: Erythrocyte sedimentation rate, CRP: C-reactive protein, S: Serum, Syn. enhan: Synovial enhancement, MRI: Magnetic resonance imaging. A significant increase in serum S100A12 levels and total magnetic resonance imaging score in systemic and polyarticular subtypes compared to oligoarticular patients with juvenile idiopathic arthritis. NS: Not significant, S: Significant, HS: Highly significant