Table 6.
Fall in serum potassium and increase in heart rate
| Four puffs | Eight puffs | |||||
|---|---|---|---|---|---|---|
| Test FP/SM | Reference FP/SM | Mean difference* | Test FP/SM | Reference FP/SM | Mean difference* | |
| Potassium | ||||||
| Maximum fall | −0.30 | −0.23 | −0.07 | −0.59 | −0.50 | −0.09 |
| (mmol l−1) | (0.22) | (0.21) | (−0.18, 0.04) | (0.26) | (0.27) | (0.20, 0.02) |
| AUC for maximum fall | −15.25 | −7.42 | −8.49 | −42.94 | −33.51 | −9.19 |
| (mmol l−1 h) | (20.12) | (30.24) | (−21.36, 4.39) | (26.86) | (29.55) | (−21.93, 3.55) |
| Heart rate | ||||||
| Maximum increase | 20.0 | 15.8 | 4.2 | 28.9 | 22.6 | 6.4 |
| (beats min−1) | (9.2) | (7.7) | (0.8, 9.2) | (11.2) | (11.1) | (1.4, 11.4) |
| AUC for maximum increase | 1086.3 | 559.4 | 526.0 | 2256.6 | 1456.5 | 809.4 |
| (beats min−1 h) | (869.2) | (774.2) | (−18.0, 1070.1) | (1185.3) | (1365.8) | (270.8, 1348.1) |
All data presented as means (SD) unless otherwise indicated.
*
Arithmetic mean (95% CI) difference between test and reference FP/SM.