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. Author manuscript; available in PMC: 2011 Jan 15.
Published in final edited form as: Cancer Res. 2010 Jan 12;70(2):697–708. doi: 10.1158/0008-5472.CAN-09-1592

Figure 4. MAA expression of ABCB5+ MMICs compared to ABCB5 tumor bulk populations.

Figure 4

(A) Representative dual-color flow cytometry analysis of malignant melanoma cells (MMC) costained for ABCB5 expression (APC, Fl4 fluorescence) and the MAAs ML-IAP, NY-ESO-1, MAGE-A, and (B) MART-1 (FITC, Fl1 fluorescence) in clinical patient-derived melanoma cells (left panel) and established G3361 melanoma cells (right panel). (C) MAA expression by ABCB5+ versus ABCB5 melanoma subpopulations (mean±SEM), as determined by dual-color flow cytometry (*: P<0.05; **: P<0.01). (D) Relative mRNA expression of TGF-β pathway members in ABCB5+ versus ABCB5 melanoma cells.