Figure 5.
Schematic representation of the pair-wise intermolecular contacts in the XRCC4-TmC:TmN-EB1 overlap complex. Chains A and B correspond to XRCC4-TmC, whereas chains C and D correspond to TmN-EB1. The hydrophobic interactions were selected based on a distance cutoff of 3.9 Å using Contact. The predicted coiled-coil heptad registration is shown for both the N- and C-terminal sequences of smooth muscle tropomyosin (37, 38). The hydrogen bonding and ionic interactions are highlighted by red circles, whereas all other interactions are non-polar interactions. The color scheme for this figure is the same as that defined in the ribbon representation shown in Figure 3.