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Immunoreactive levels of MARCO and SR-A remain elevated in TLR9–/– mice compared with TLR9+/+ mice after CpG treatment. ELISA analysis of SR-A (a) and MARCO (b) in whole-lung samples from Aspergillus-sensitized and conidium-challenged TLR9+/+ and TLR9–/– mice. Both groups were treated with IN CpG or IP CpG on alternate days from day 14 to day 28 after conidium challenge. Means ± SEM; n = 5/group/time point. ∗ p ≤ 0.05 vs. IN CpG TLR9+/+ group.
