Figure 4. N-cadherin homophilic binding does not enhance HVA Ca²⁺ currents in St 35 neurons.

A) Voltage clamp recordings from St 35 ciliary neurons plated on control Con A substrate or on Fc-N-cadherin substrate (Fc-N-cadherin). St 35 neurons show no substantial modulation of HVA Ca²⁺ current when plated on Fc-N-cadherin with respect to control (control circles 17 ± 1.5, n=6; Fc-N-cadherin substrate squares 18.9 ± 2.5, n=7, p=0.27). Values are expressed as mean ± SE. B) Summary histogram of the average peak Ca²⁺ current density recorded from St 35 and St 40 neurons plated on Con A or on an N-cadherin substrate (data from Fig 3A and 4A). * p<0.01