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. 2010 May 12;5:35. doi: 10.1186/1748-717X-5-35

Table 2.

Univariate analysis of the dosimetric parameters(MLD, NTCP, V5-V60) for predicting development of SARP for 94 patients

Variable Median(range) No RP(n = 83) RP(n = 11) pvalue*
MLD 11.59(6.53-18.11) Gy Inline graphic = 11.26, SD = 2.81 Inline graphic = 14.91, SD = 2.91 0.001
NTCP 2.33% (0.51-9.68%) Inline graphic = 2.51, SD = 1.73 Inline graphic = 5.94, SD = 2.40 0.001
V5 58.73% (32.89-97.65%) Inline graphic = 58.43, SD = 16.57 Inline graphic = 69.23, SD = 12.47 0.006
V10 42.16%(25.28-83.34%) Inline graphic = 41.13, SD = 12.69 Inline graphic = 52.42, SD = 11.05 0.001
V15 29.53%(16.46-58.51%) Inline graphic = 28.94, SD = 9.12 Inline graphic = 38.30, SD = 7.65 0.005
V20 18.15% (9.46-31.08%) Inline graphic = 18.59, SD = 6.03 Inline graphic = 28.02, SD = 7.09 0.002
V25 12.96% (5.90-26.26%) Inline graphic = 12.88, SD = 4.42 Inline graphic = 20.91, SD = 6.98 0.001
V30 10.00% (4.68-21.43%) Inline graphic = 9.72, SD = 3.45 Inline graphic = 15.69, SD = 6.00 0.008
V35 9.92% (3.89-18.65%) Inline graphic = 7.57, SD = 2.86 Inline graphic = 11.95, SD = 4.64 0.011
V40 8.20% (3.29-13.61%) Inline graphic = 5.91, SD = 2.48 Inline graphic = 9.26, SD = 3.75 0.015
V45 7.42% (2.73-10.99%) Inline graphic = 4.41, SD = 2.25 Inline graphic = 6.54, SD = 3.47 0.007
V50 7.07%(1.94-8.82%) Inline graphic = 3.15, SD = 1.94 Inline graphic = 4.89, SD = 2.15 0.007
V55 6.75% (1.33-6.32%) Inline graphic = 2.03, SD = 1.65 Inline graphic = 3.19, SD = 1.75 0.033
V60 5.76% (0.80-4.20%) Inline graphic = 1.23, SD = 1.09 Inline graphic = 1.66, SD = 1.15 0.039

Abbreviation: MLD = mean lung dose; NTCP = normal tissue complication probability; SARP = severe acute radiation pneumonitis; * Comparison of dosimetric factors between patients who developed severe acute RP and those who did not