Skip to main content
. 2010 Jun 11;5(6):e11076. doi: 10.1371/journal.pone.0011076

Figure 2. Proliferation after withdrawal of Hsp90 inhibitors.

Figure 2

Cells were treated for 48 h with the indicated concentration of inhibitor, which was then removed. Viable cell counts were then determined at the indicated times after inhibitor removal. A, H69 cells treated with geldanamycin; B, H187 cells treated with geldanamycin; C, H69 cells treated with 17-AAG. D, H69 cells treated with 100 nM geldanamycin for 4, 12 or 24 h. E, H69 cells were treated for 48 h with 100 nM geldanamycin in the absence or presence of 100 µM Z-VAD-FMK, a general caspase inhibitor. Z-VAD-FMK treatment was started 1 h before the addition of geldanamycin. F, U87MG cells treated with geldanamycin.