Table 2.
| ||
---|---|---|
entry | conditions | 8:9:10a |
1 | Pd/C, H2, EtOH | 0:1:1 |
2 | PtO2, H2, MeOH | 0:2:1 |
3 | Pd/C, H2, PhH, Et3SiH | 1:1:2 |
4 | PdBaSO4, H2, EtOH | 2:1:1 |
5 | Pd/C, H2, toluene, 110 °Cb | NR |
6 | (cod)(pyr)(PCy3)IrPF6, H2 | 1:0:0c |
Ratio determined by 1H NMR spectroscopy;
Reaction exposed to H2 for 5 minutes and was then sealed;
99% isolated yield.