Table 3.
Expression of regulatory and effector proteins
| Regulatory/effector protein | Molecular weight (kDa) | Dose (ng)/time (h) | Upregulation/downregulation | Max increase/decrease |
|---|---|---|---|---|
| pJNK | 46 | 100/8 | Upregulation | 4 ± 0.17; 4 ± 0.13 |
| p38 | 38 | 100/8 | Upregulation | 4 ± 0.12; 4 ± 0.03 |
| ERK1/2 | 42/44 | 100/8 | No significant change | |
| p53 | 53 | 100/8 | Upregulation | 4.11 ± 0.08; 4.2 ± 0.15 |
| Bax | 21 | 100/8 | Upregulation | 4.17 ± 0.18; 4.28 ± 0.15 |
| Bcl-2 | 26 | 100/8 | Downregulation | 6-fold ↓ |
| Cytochrome C | 10 | 100/8 | Upregulation | 4-fold ↑ |
| Apaf-1 | 130 | 100/8 | Upregulation | 4.2 ± 0.1; 4 ± 0.2 |
| Caspase 9 | 48/37 | 100/8 | Upregulation | 8-fold |
| Caspase 3 | 32/20/17 | 100/8 | Upregulation | 9-fold |