Figure 1.

(a) The ratio of reduced (GSH) to oxidized (GSSG) forms of glutathione in ischaemia–reperfused (I-R) and contused muscle is illustrated at 8 h and 3 days postinjury. A decrease in GSH:GSSG indicates elevated oxidative stress. (b) Lipid peroxidation in I-R and contused muscle. Lipid peroxidation was quantified using the TBARS assay to measure levels of malondialdehyde (MDA). * denotes a significant difference relative to uninjured control, P<0.05. ø denotes a significant difference from earlier time point within the same experimental group, P<0.05. ψ denotes a significant difference between contusion and IR-contusion at same time point, P<0.05. Error bars represent the SE of the mean (SEM, n=8 per group).