Figure 3.

(A and B) Ribbon representation of PgHsp70 comparative model, Helix A highlighted in a box. The region above Helix A corresponds to the substrate binding domain (SBD) and the region below, to the nucleotide binding domain (NBD). Interdomain linker represented as red C_α trace. (C) Detailed view of interactions between SBD (C_α trace in red orange) and NBD (C_α trace in Cyan) and few discontinuous residues without C_α trace, side chains of residues identical or conserved to the template in blue, red, yellow or dark grey for +, −, polar, or nonpolar. PgHsp70 residues not conserved with respect to the template residues are shown in green.