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. Author manuscript; available in PMC: 2010 Jun 14.
Published in final edited form as: JAMA. 2009 May 27;301(20):2099–2110. doi: 10.1001/jama.2009.723

Table 5. 12-Month Medication and Health Care Use.

Variable No (%) of Patients with Any Use Over 12 Months Amount of Use in Entire Sample Over 12 Months Mean (SD); Median (Range) P Value a
Intervention Group (n = 123) Usual Care Group (n = 127) Intervention Group (n = 123) Usual Care Group (n = 127)
Medication use, mo
 Antidepressants 121 (98) 54 (43) 9.2 (4.2); 12 (0-12) 2.0 (3.3); 0 (0-12) < .001
 Tricyclics b 32 (26) 35 (28) 1.2 (2.7); 0 (0-12) 1.2 (2.6); 0 (0-12) .98
 Other psychotropics 20 (16) 16 (13) 0.7 (2.2); 0 (0-12) 0.7 (2.2); 0 (0-12) .89
 Opioid analgesics 67 (54) 67 (53) 3.5 (4.6); 1 (0-12) 3.0 (4.2); 1 (0-12) .35
 Other analgesics c 74 (60) 82 (66) 2.5 (3.1); 1 (0-12) 2.8 (3.4); 1 (0-12) .44
Health care use, No.
 Outpatient visits
  Primary care 115 (94) 119 (94) 6.3 (5.8) 5 (0-35) 5.9 (5.3); 4 (0-33) .16
  Medical specialty 52 (42) 53 (42) 1.3 (2.3); 0 (0-16) 1.6 (2.8); 0 (0-19) .03
  Surgical specialty 77 (63) 86 (68) 2.7(4.0); 1 (0-24) 2.4 (3.5); 1 (0-26) .10
  Mental health 31 (25) 21 (17) 1.6 (7.9); (0-82) 0.7 (2.9); 0 (0-24) < .001
  Other 45 (37) 53 (42) 1.4 (3.4); 0 (0-23) 1.2 (2.4); 0 (0-18) .16
 Emergency dept visits 61 (50) 59 (46) 1.8 (3.5); 0 (0-27) 1.2 (2.1); 0 (0-14) < .001
 Time in hospital, d 25 (20) 18 (14) 1.5 (5.9); 0 (0-49) 0.8 (2.5); 0 (0-15) < .001
a

Differences between group means were compared using t-test for amount of medication use and Poisson modeling for amount of health care use

b

Typically low-dose (< 100 mg amitriptyline or equivalent) rather than antidepressant dose level

c

The use of “other analgesics” may be underestimated since simple analgesics are often obtained without a prescription and would not be captured by electronic prescribing data.