Appendix. Antidepressant Selection and Dosing Details in SCAMP.

Priority	Indications and Precautions	Class*	Drug	Dose (in mg)
				Initial	Dose Increases
1	Avoid if cardiovascular disease, abnormal ECG, or hypertension not well controlled	SNRI	Venlafaxine	75	150, 225
2	SSRI of choice	SSRI	Fluoxetine	20	30, 40
2	SSRI of choice if cardiovascular disease		Sertraline	50	100, 150
3	If failed first SSRI (fluoxetine or sertraline)		Citalopram	20	30, 40
4	If obese or weight gain/sexual side effects	Other	Bupropion	200	300, 400
4	If insomnia a problem. Avoid if obese.		Mirtazapine	15	30, 45
5	Avoid if cardiovascular disease, abnormal ECG, or hypertension not well controlled	TCA	Nortriptyline	25	50, 75

^*SNRI = serotonin-norepinephrine reuptake inhibitor. SSRI = selective serotonin reuptake inhibitor. TCA = tricyclic antidepressant.