TABLE 5.
IL-10 −1082C→T is related to lower respiratory tract infection in men1
| Type of infection | IL-10 −1082C→T | n | Incidence2 | RR (95% CI) | P for RR3 | P overall3 |
| All lower respiratory | T/T | 50 | 0.61 | 3.36 (1.28, 8.83)4 | 0.01 | — |
| T/C | 66 | 0.80 | 3.99 (1.55, 10.26)4 | 0.01 | — | |
| C/C | 26 | 0.20 | 1 | — | <0.01 |
1
RR, rate ratio.
2
A negative binomial distribution was assumed for regression analysis of infection incidence. Incidence is per person-year.
3
For analysis between men and adjusted for the natural log offset of time in the intervention study and supplementation (α = 0.05). Adjustment for baseline zinc did not significantly alter the association.
4
Compared with the C/C genotype group.