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A: Unadjusted mean scores of the Bayley Mental Development Index at 24 mo of age (MDI-24) by maternal MTHFR 677 genotype (P for trend = 0.01; TT compared with CC or CT; P < 0.05). B: Unadjusted mean MDI-24 scores by child MTHFR 677 genotype (P for trend = 0.22).