Table 2.
Echocardiographic findings in control (n = 38) and thalassemia patients (n = 38) in the study population. Data are presented as mean ± SEM per body surface area (m2). P value < 0.05 is considered statistically significant.
| Parameter | Control | Thalassemia | P-value |
|---|---|---|---|
| IVS/BSA (cm/M2) | 0.446 ± 0.219 | 0.659 ± 0.26 | <0.001* |
| PW/BSA (cm/M2) | 0.437 ± 0.214 | 0.659 ± 0.235 | <0.001* |
| LVEDD/BSA (mm/M2) | 2.170 ± 0.57 | 3.995 ± 0.48 | <0.035* |
| LVESD/BSA (mm/M2) | 2.217 ± 0.45 | 2.40 ± 0.54 | <0.001* |
| FS (%) | 31.329 ± 3.810 | 33.878 ± 4.944 | 0.107 |
| LVEF (%) | 57.656 ± 6.641 | 58.454 ± 6.504 | 0.103 |
| E wave/BSA (cm/sec) | 57.532 ± 12.959 | 70.818 ± 10.139 | <0.027* |
| A wave/BSA (cm/sec) | 46.330 ± 9.851 | 44.646 ± 7.776 | 0.109 |
| E/A ratio | 1.233 ± 0.27 | 1.54 ± 0.235 | <0.021 |
| DT/BSA (msec) | 167.123 ± 19.143 | 150.234 ± 20.023 | <0.01 |
| IVRT/BSA (msec) | 75.474 ± 5.83 | 60.647 ± 6.770 | <0.01 |
| Tricuspid velocity/BSA (m/sec) | 1.453 ± 0.471 | 2.993 ± 0.569 | <0.01 |
Abbreviations: IVS, interventricular septal thickness; Pw, posterior wall thickness; LVEDD, left ventricle end diastolic diameter; LVESD, left ventricle end systolic diameter; FS, fractional shortening; EF, left ventricle ejection fraction; E wave, mitral E wave peak velocity; A wave, mitral A wave peak velocity; DT, E wave deceleration time; IVRT, isovolumic relaxation time; TR, tricuspid velocity.