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. Author manuscript; available in PMC: 2010 Jun 14.
Published in final edited form as: Antivir Ther. 2008;13(7):851–862.

Figure 5.

Figure 5

ISG expression induced by CIFN in human hepatocytes is distinct from IFN-α2a and PEG-IFN. The figure shows Principle Component Analysis (PCA) of the IFN-regulated transcriptome from PH5CH8 cells that were cultured in the presence of media alone (CTRL) or media containing the Cmax of each IFN for 4, 8 or 20 hours as indicated. The greatest determinant of inter-sample variance lies on the X coordinate (the first principal component), the second greatest variance on the Y coordinate (the second principal component), and the third greatest principle component on the Z coordinate. Higher-order principal components contributing less to intersample variability are ignored.