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. Author manuscript; available in PMC: 2010 Jun 14.
Published in final edited form as: Sleep. 2007 Apr 1;30(4):389–400. doi: 10.1093/sleep/30.4.389

Figure 7.

Figure 7

Sleep deprivation increases resistance to infection. A. Left panel: Representative bacterial cultures obtained from Canton- S flies infected with E. coli immediately following a 4h deprivation (DEP; lower), or from handled controls (HC; upper). Plates are a 1:10 dilution of the homogenate. Right panel: the average number of colony forming units (cfu) per fly is plotted for flies from several strains including CS, y w, and rosy (see text; * = P <0.05; n=9) B. Effect of deprivation is limited to a time of day when flies are predicted to be resting. y w flies were sleep deprived and infected at the times indicated. Cfu/fly is significantly greater in HC as compared to DEP at ZT8 (* = P <0.05; n=4). No significant difference is observed between HC and DEP at ZT2, when flies are predicted to be active.