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. Author manuscript; available in PMC: 2010 Jun 14.
Published in final edited form as: Psychopharmacology (Berl). 2009 Sep 17;207(3):381–390. doi: 10.1007/s00213-009-1666-5

Figure 2.

Figure 2

illustrates operant responding during the Bupropion and Nicotine Pretreatment Phase. Panel A illustrates active lever responses over testing sessions for rats in the five treatment groups. Panel B illustrates inactive lever responses over testing sessions for each group. Panel C illustrates the effects of acute (first drug-pretreatment test) and chronic (seventh drug pretreatment test) drug administration on active lever responding in each drug/dose condition. * indicates that responding in chronic test differs significantly from responding on the acute test, p<0.05.