Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic representation of groups, number of subjects, and treatments from each experiment.
| Group | n | Experiment 1 | Experiment 2 | ||
|---|---|---|---|---|---|
| Acquisition (Sessions 1–23) | Drug Pretreatment (Sessions 24–30) | nAChR (Sessions 31–35) | NE-R (Sessions 41–52) | ||
| SAL | 8 | Active Lever: VS (FR1, FR2, FR5) | SAL (IP/SC) | 0, 0.05, 0.1 mg/kg mecamylamine | 0, 0.1, 0.3, 1 mg/kg prazosin |
| 0.4 NIC | 8 | 0.4 NIC | |||
| 3 BUP | 9 | 3 BUP | 0, 2.5, 5, 10 mg/kg propranolol | ||
| 10 BUP | 9 | 10 BUP | |||
| 30 BUP | 8 | 30 BUP | |||
