TABLE 5.
DNA damage response proteins in Acinetobacter spp.
| Protein | Function and comment |
|---|---|
| E. coli DNA damage proteins not found in Acinetobacter spp. | |
| DinB | DNA polymerase II; error-prone polymerase involved in SOS mutagenesis |
| σ38 | Stationary phase/stress response σ factor |
| SulA | Cell division inhibitor; induced during SOS response |
| FtsEX | Transporter of unknown function; induced during SOS response |
| LexA | Transcriptional regulator; primary regulator of SOS response |
| Recognized DNA damage response proteins in Acinetobacter spp. | |
| UmuC | DNA polymerase V subunit; truncated to UmuC* (first 64 residues of UmuC) in A. baylyi ADP1 |
| UmuDAb | DNA polymerase V subunit; 50% longer than E. coli UmuD protein, contains LexA-like protease recognition site, regulates expression of DdrR in response to DNA damage |
| DdrR | Unknown function; upregulated following induction of DNA damage in A. baylyi ADP1, found only in Acinetobacter spp. |
| RecA | Recombination protein A; upregulated following induction of DNA damage in A. baylyi ADP1, required for DNA damage-inducible regulation of DdrR |