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Abilities of chimeric HBcΔ-derived VLPs to package nucleic acids. Native 1% agarose electrophoresis gels in Tris-acetate-EDTA (TAE) buffer (A and B) and Ouchterlony's double radial immunodiffusion (C and D) of purified HBcΔ-derived VLPs stained by ethidium bromide (EtBr) (A and C) and Coomassie blue (B and D). Lanes and spots: 1, HBcΔ; 2, HBcΔ-pre-S1; 3, HBcΔ-HCV core; 4, HBcΔ-pre-S1-HCV core; M, 1-kb ladder (Fermentas, Lithuania).
