TABLE 1.
LPS and PAM do not induce cytokine inhibitorsa
| Cytokine | Cytokine concn (ng/ml) |
||
|---|---|---|---|
| Vehicle | LPS | PAM | |
| IL-1 SRII | 9.0 ± 1.6 | 7.0 ± 0.5 | 4.2 ± 0.5 |
| IL-1 receptor antagonist | 4.1 ± 1.7 | 3.0 ± 1.2 | 4.7 ± 0.9 |
| TNF SRII | 2.0 ± 0.4 | 1.3 ± 0.1 | 3.2 ± 0.9 |
a
Plasma was collected from human whole blood stimulated with LPS (50 ng/ml), PAM (1000 ng/ml), or vehicle for 24 h. In contrast to the proinflammatory mediators, there was no significant increase in any of the cytokine inhibitors. Values represent the mean ± SEM (n = 5 to 9).