Nomenclature	PDE5A	PDE7A	PDE7B	PDE8A	PDE8B
Other names	PDE V, cGMP-specific PDE	HCP1	–	High-affinity cAMP- specific and IBMX- insensitive PDE	–
Ensembl ID	ENSG00000138735	ENSG00000104732	ENSG00000171408	ENSG00000073417	ENSG00000113231
Rank order of affinity	cGMP > cAMP	cAMP >> cGMP (Michaeli et al., 1993)	cAMP >> cGMP (Gardner et al., 2000)	cAMP >> cGMP (Fisher et al., 1998a)	cAMP >> cGMP (Hayashi et al., 1998)
Activators	PKA (Corbin et al., 2000), PKG (Corbin et al., 2000)	–	–	–	–
Selective inhibitors	T0156 (9.5, Mochida et al., 2002), sildenafil (9.0, Turko et al., 1999), SCH51866 (7.2, Vemulapalli et al., 1996), zaprinast (6.8, Turko et al., 1999)	BRL50481 (6.7, Smith et al., 2004)	Dipyridamole (5.7–6.0, Gardner et al., 2000); Sasaki et al., 2000), SCH51866 (5.8, Sasaki et al., 2000)	Dipyridamole (5.1, Fisher et al., 1998a)	Dipyridamole (4.3, Hayashi et al., 1998)